Top five news stories selected by Animal Health SmartBrief readers in the past week.
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Neste Blog realizamos: 1 - Atualização sobre SAÚDE PÚBLICA, PESQUISA BIOMÉDICA E BIOSSEGURANÇA. 2 - Atualização sobre a ocorrência de Doenças de importância em animais de laboratório e outras espécies. 3 - Troca de Informações sobre Doenças Infecciosas, Zoonoses, Licenciamento Ambiental, Defesa Sanitária Animal, Vigilância Sanitária, Boas Práticas de Laboratório e demais assuntos relacionados à sanidade e Saúde Pública.
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quarta-feira, 22 de dezembro de 2010
Kroger announces a recall of pet-food varieties
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FDA works with drug companies to change antibiotic practices
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- FDA works with drug companies to change antibiotic practices
The Food and Drug Administration is reportedly in talks with at least one drug company in an effort to convince pharmaceutical firms to voluntarily stop providing antibiotics for the purpose of promoting livestock growth. FDA officials have said the agency, which is concerned that overuse of antibiotics may contributed to drug-resistant bacteria strains, prefers a voluntary approach rather than the more time-consuming process of creating laws to restrict the use of the drugs. The Des Moines Register (Iowa) (12/19)
- Researchers identify possible cause of genital cancer in horses
A group of researchers have identified a papillomavirus infection as a likely cause of genital cancer in horses. The infection is similar to the virus that can cause certain human genital cancers, including cervical cancer, according to the research published in the current edition of the Equine Veterinary Journal. PhysOrg.com (12/20)
- 4 Texas veterinarians win loan-repayment grants
The Department of Agriculture is providing four veterinarians in Texas with loan-repayment funds under a federal program designed to address a nationwide shortage of large-animal veterinarians. The Veterinary Medicine Loan Repayment Program aims to repay the student loans of eligible veterinarians in exchange for their services in rural veterinary shortage areas. San Angelo Standard-Times (Texas) (12/19)
- Other News
- Veterinarian shaves head to raise funds for homeless pets
KCBY-TV (North Bend, Ore.) (12/20)
- China convicts 8 people of fake rabies-vaccine sales
Forbes/The Associated Press (12/20)
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- Report underscores growing problem of unwanted horses in the U.S.
A report published in the Journal of American Sciences indicated that the number of abandoned horses in the U.S. totals about 100,000 per year, driven in part by the economic downturn and the shutdown of slaughterhouses in 2007. According to the report, caring for each horse costs an average of $3,648 per year. One shelter near Boston reports record numbers of surrenders by horse owners since the downturn began three years ago.Lexington Herald-Leader (Ky.) (12/20) , Boston Herald/The Associated Press (12/20)
- Canine distemper is prevalent in Troy, N.Y.
Eighteen foxes in Troy, N.Y., reportedly have been found in the past 20 days with canine distemper, which officials say could put pets at risk for contracting the potentially fatal disease. Area residents are advised to ensure their pets are up-to-date on distemper vaccinations as well as keep them from contact with foxes and other wild animals. WRGB-TV (Albany (N.Y) (12/17)
- Diseases tied to canine obesity are on the rise
Dogs in North America increasingly are putting on excess weight, resulting in more canines developing serious illnesses such as osteoarthritis, diabetes, pancreatitis, heart disease and respiratory issues. A Texas veterinarian attributes the growing problem of pet obesity to a lack of adequate exercise and improper diet. El Paso Times (Texas) (12/20)
- Experts emphasize importance of regular exercise for dogs: With about 45% of U.S. dogs suffering from obesity, according to the Association for Pet Obesity Prevention, experts are urging canine owners to provide their pets with regular exercise and workouts especially during the holidays. Experts recommend consulting a veterinarian about safe workout routines to avoid the risk of overworking dogs. The Oregonian (Portland) (12/20)
- Other News
- Dogs become comforting part of therapy sessions
The Wall Street Journal (12/20)
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- Don't worry about being humble
It doesn't matter if bosses are full of themselves as long as they're also generous with giving credit to others, says Linda Hill, a Harvard professor and author of several books on business leadership. Good leaders know that their job is to ensure that all their employees excel at what they do, and see their successes as reflections of their managerial abilities. "You should lead as if everybody matters, because everybody does," Hill says. Inc.com (12/17)
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- Food safety bill appears to be set to clear Congress
The House is expected today to approve the Food Safety Modernization Act, which the Senate passed unanimously on Sunday. The bill would go to President Barack Obama for his signature. Los Angeles Times (12/21) , FoodSafetyNews.com (12/21)
- Arkansas bill would make farriers and horse teeth floaters legal
Legislators in Arkansas have introduced a bill that aims to allow farriers and horse teeth floaters to legally practice in the state. The bill would also allow acupuncture to be performed on horses if it is done under a veterinarian's supervision. An official with the Arkansas Veterinary Medical Association said his organization will take a look at the measure and offer recommendations. New England Cable News (Boston)/Arkansas Democrat-Gazette (Little Rock)/The Associated Press (12/20)
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- Contamination fears prompt recall of certain Kroger pet treats
Kroger has recalled certain lots of its Old Yeller, Kroger Value and Pet Pride dog and cat food varieties because they possibly contain aflatoxin, a toxic chemical that has been linked to a rash of dogs who became ill or died in 2005 after eating contaminated products from Diamond Pet Foods. According to this article, which cites AVMA, Diamond Pet Foods eventually paid consumers $3.1 million to settle a lawsuit filed over the incidents. WalletPop(12/20)
- Modern medicine provides pricey pet treatments
SmartMoney.com (12/21)
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- Practice management and staff training
The AVMA has a set of five books, downloadable in PDF format, to help assist in staff training and managing your practice. View AVMA's Practice management and staff training resources.
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terça-feira, 21 de dezembro de 2010
Drug-Resistant Genes Spread among Bacteria
Unlike other superbugs, a new class of antibiotic-resistant bacteria are gaining their power from easily transferable genes such as NDM-1
In the fight to stay alive, many bacteria, such as MRSA, have developed resistance to commonly used antibiotics. But other bacteria are using a more insidious type of resistance: that imbued by transferable genes, which can spread among commonly circulating strains.
One of these genetic elements, NDM-1 (New Delhi metallo-beta-lactamase 1), is an enzyme-based defense that renders a bacterium immune to beta-lactam-based antibiotics, which include penicillin, as well as carbapenems (often used as a last resort antibiotic against Escherichia coli infections), cephems (such as cephalosporins and cephamycins) and monobactams, making treatment extremely difficult. The trait was first identified in 2008 (in a patient with Klebsiella pneumoniae), and instances of NDM-1–positive infections are now not uncommon in India, Pakistan and Bangladesh. Cases also have been documented in Brazil, Canada, Japan, the U.K. and the U.S.
A new essay published in the December 16 issue of The New England Journal of Medicine revisits the issue, highlighting the potential that NDM-1 and other antibiotic-busting genes have to disable much of our current pharmaceutical arsenal.
"The spread of these organisms has prompted widespread concern because some of them are resistant to all antimicrobial agents except the polymyzins," Robert Moellering, of Harvard Medical School and Beth Israel Deaconess Medical Center, wrote in the perspective piece.
Initial cases of NDM-1 seemed to be only found among patients who had received medical care in India, where antibiotic use is less regulated. But more recent findings have suggested some NDM-1–positive patients in the U.K. might have picked up a resistant strain without traveling abroad.
These genes do not need an exotic infection to wreak havoc in a patient. They can be picked up by "all sorts of bugs we're all walking around with in our guts," says Brandi Limbago, of the Division of Healthcare Quality Promotion at the U.S. Centers for Disease Control and Prevention. But once the resistant genetic material enters the bacterium, "it produces an enzyme that attacks the antibiotic and makes it nonfunctional—they basically chew it up," she explains. These infections are not always deadly, but "in the right host," such as one with a weakened immune system or inserted medical equipment (including catheters), "those patients become infected with these organisms," Limbago says. "And if you don't have the right tools to treat them, that's when you run into trouble."
Newer antibiotics, such as cephalosporins and carbapenems as well as beta-lactamase inhibitors, seemed like an effective strategy against these bacterial tactics. But these have "simply been met with the evolution of new beta-lactamases, often through mutations, that inactivate these antibiotics," Moellering wrote. Currently, there are some 890 such known enzymes, "far more than the antibiotics developed to combat them."
Misuse of antibiotics has been a major driver of resistance—both in strain-specific bacteria and gene-based resistance. "Prudent antibiotic use should always be the goal," Limbago says. But "once the gene is there, it's there. And at that point, the genie's out of the bottle."
After resistance has started circulating, surveillance and infection control become the key tools to fight further spread. The U.S. does not have KPC- or NDM-1–specific strategies, but offers recommendations for all CRE-positive infections. The government also does not require hospitals to report CRE cases, but even so, infections have been confirmed in at least 35 states. Rather than being cautious about the growing concern over NDM-1 and other resistance genes, Limbago suggests that, "in some places in the U.S. people are not getting as excited about this as they should."
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